You can use either resample or Grouper (which resamples under the hood).
First make sure that the datetime column is actually of datetimes (hit it with pd.to_datetime). It's easier if it's a DatetimeIndex:
In [11]: df1
Out[11]:
abc xyz
Date
2013-06-01 100 200
2013-06-03 -20 50
2013-08-15 40 -5
2014-01-20 25 15
2014-02-21 60 80
In [12]: g = df1.groupby(pd.Grouper(freq="M")) # DataFrameGroupBy (grouped by Month)
In [13]: g.sum()
Out[13]:
abc xyz
Date
2013-06-30 80 250
2013-07-31 NaN NaN
2013-08-31 40 -5
2013-09-30 NaN NaN
2013-10-31 NaN NaN
2013-11-30 NaN NaN
2013-12-31 NaN NaN
2014-01-31 25 15
2014-02-28 60 80
In [14]: df1.resample("M", how='sum') # the same
Out[14]:
abc xyz
Date
2013-06-30 40 125
2013-07-31 NaN NaN
2013-08-31 40 -5
2013-09-30 NaN NaN
2013-10-31 NaN NaN
2013-11-30 NaN NaN
2013-12-31 NaN NaN
2014-01-31 25 15
2014-02-28 60 80
Note: Previously pd.Grouper(freq="M") was written as pd.TimeGrouper("M"). The latter is now deprecated since 0.21.
I had thought the following would work, but it doesn't (due to as_index not being respected? I'm not sure.). I'm including this for interest's sake.
If it's a column (it has to be a datetime64 column! as I say, hit it with to_datetime), you can use the PeriodIndex:
In [21]: df
Out[21]:
Date abc xyz
0 2013-06-01 100 200
1 2013-06-03 -20 50
2 2013-08-15 40 -5
3 2014-01-20 25 15
4 2014-02-21 60 80
In [22]: pd.DatetimeIndex(df.Date).to_period("M") # old way
Out[22]:
<class 'pandas.tseries.period.PeriodIndex'>
[2013-06, ..., 2014-02]
Length: 5, Freq: M
In [23]: per = df.Date.dt.to_period("M") # new way to get the same
In [24]: g = df.groupby(per)
In [25]: g.sum() # dang not quite what we want (doesn't fill in the gaps)
Out[25]:
abc xyz
2013-06 80 250
2013-08 40 -5
2014-01 25 15
2014-02 60 80
To get the desired result we have to reindex...