Here's a simple Python 3 implementation based on this answer (which, in turn, is based on the solution proposed in the accepted answer)
def is_clockwise(points):
# points is your list (or array) of 2d points.
assert len(points) > 0
s = 0.0
for p1, p2 in zip(points, points[1:] + [points[0]]):
s += (p2[0] - p1[0]) * (p2[1] + p1[1])
return s > 0.0