Generally you can't change styles programmatically; you can set the look of a screen, or part of a layout, or individual button in your XML layout using themes or styles. Themes can, however, be applied programmatically.
There is also such a thing as a StateListDrawable
which lets you define different drawables for each state the your Button
can be in, whether focused, selected, pressed, disabled and so on.
For example, to get your button to change colour when it's pressed, you could define an XML file called res/drawable/my_button.xml
directory like this:
<?xml version="1.0" encoding="utf-8"?>
<selector xmlns:android="http://schemas.android.com/apk/res/android">
<item
android:state_pressed="true"
android:drawable="@drawable/btn_pressed" />
<item
android:state_pressed="false"
android:drawable="@drawable/btn_normal" />
</selector>
You can then apply this selector to a Button
by setting the property android:background="@drawable/my_button"
.