CHARINDEX()
searches for a substring within a larger string, and returns the position of the match, or 0 if no match is found
if CHARINDEX('ME',@mainString) > 0
begin
--do something
end
Edit or from daniels answer, if you're wanting to find a word (and not subcomponents of words), your CHARINDEX
call would look like:
CHARINDEX(' ME ',' ' + REPLACE(REPLACE(@mainString,',',' '),'.',' ') + ' ')
(Add more recursive REPLACE() calls for any other punctuation that may occur)