using pywin32:
from win32com.client import Dispatch
session = Dispatch('MAPI.session')
session.Logon('','',0,1,0,0,'exchange.foo.com\nUserName');
msg = session.Outbox.Messages.Add('Hello', 'This is a test')
msg.Recipients.Add('Corey', 'SMTP:[email protected]')
msg.Send()
session.Logoff()