[pandas] How to properly apply a lambda function into a pandas data frame column

You need mask:

sample['PR'] = sample['PR'].mask(sample['PR'] < 90, np.nan)

Another solution with loc and boolean indexing:

sample.loc[sample['PR'] < 90, 'PR'] = np.nan

Sample:

import pandas as pd
import numpy as np

sample = pd.DataFrame({'PR':[10,100,40] })
print (sample)
    PR
0   10
1  100
2   40

sample['PR'] = sample['PR'].mask(sample['PR'] < 90, np.nan)
print (sample)
      PR
0    NaN
1  100.0
2    NaN

sample.loc[sample['PR'] < 90, 'PR'] = np.nan
print (sample)
      PR
0    NaN
1  100.0
2    NaN

EDIT:

Solution with apply:

sample['PR'] = sample['PR'].apply(lambda x: np.nan if x < 90 else x)

Timings len(df)=300k:

sample = pd.concat([sample]*100000).reset_index(drop=True)

In [853]: %timeit sample['PR'].apply(lambda x: np.nan if x < 90 else x)
10 loops, best of 3: 102 ms per loop

In [854]: %timeit sample['PR'].mask(sample['PR'] < 90, np.nan)
The slowest run took 4.28 times longer than the fastest. This could mean that an intermediate result is being cached.
100 loops, best of 3: 3.71 ms per loop