Presenting to you
left.merge(right, how='cross')
import pandas as pd
pd.__version__
# '1.2.0'
left = pd.DataFrame({'col1': [1, 2], 'col2': [3, 4]})
right = pd.DataFrame({'col3': [5, 6]})
left.merge(right, how='cross')
col1 col2 col3
0 1 3 5
1 1 3 6
2 2 4 5
3 2 4 6
Indexes are ignored in the result.
Implementation wise, this uses the join on common key column method as described in the accepted answer. The upsides of using the API is that it saves you a lot of typing and handles some corner cases pretty well. I'd almost always recommend this syntax as my first preference for cartesian product in pandas unless you're looking for something more performant.