Try:
g = pd.DataFrame(['A','B','A','C','D','D','E'])
# Group by the contents of column 0
gg = g.groupby(0)
# Create a DataFrame with the counts of each letter
histo = gg.apply(lambda x: x.count())
# Add a new column that is the count / total number of elements
histo[1] = histo.astype(np.float)/len(g)
print histo
Output:
0 1
0
A 2 0.285714
B 1 0.142857
C 1 0.142857
D 2 0.285714
E 1 0.142857