I know it's not the asnwer to the precise question (Chrome Developer Tools) but I'm using this workaround with success: http://www.telerik.com/fiddler
(pretty sure some of the web devs already know about this tool)
Full docs: http://docs.telerik.com/fiddler/KnowledgeBase/AutoResponder
PS. I would rather have it implemented in Chrome as a flag preserve after reload
, cannot do this now, forums and discussion groups blocked on corporate network :)