SyntaxFix

[python] How to change a single value in a NumPy array?

Is this what you are after? Just index the element and assign a new value.

A[2,1]=150

A
Out[345]: 
array([[ 1,  2,  3,  4],
       [ 5,  6,  7,  8],
       [ 9, 150, 11, 12],
       [13, 14, 15, 16]])

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