Referring to Gamaliel 's answer: $args is an array of the arguments that are passed into a script at runtime - as such cannot be used the way Gamaliel is using it. This is actually working:
$myPath = 'C:\whatever.file'
# get actual Acl entry
$myAcl = Get-Acl "$myPath"
$myAclEntry = "Domain\User","FullControl","Allow"
$myAccessRule = New-Object System.Security.AccessControl.FileSystemAccessRule($myAclEntry)
# prepare new Acl
$myAcl.SetAccessRule($myAccessRule)
$myAcl | Set-Acl "$MyPath"
# check if added entry present
Get-Acl "$myPath" | fl