install exceljs and use the following code,
var Excel = require('exceljs');
var wb = new Excel.Workbook();
var path = require('path');
var filePath = path.resolve(__dirname,'sample.xlsx');
wb.xlsx.readFile(filePath).then(function(){
var sh = wb.getWorksheet("Sheet1");
sh.getRow(1).getCell(2).value = 32;
wb.xlsx.writeFile("sample2.xlsx");
console.log("Row-3 | Cell-2 - "+sh.getRow(3).getCell(2).value);
console.log(sh.rowCount);
//Get all the rows data [1st and 2nd column]
for (i = 1; i <= sh.rowCount; i++) {
console.log(sh.getRow(i).getCell(1).value);
console.log(sh.getRow(i).getCell(2).value);
}
});