strace lists all system calls done by the process it's applied to. If you don't know what system calls mean, you won't be able to get much mileage from it.
Nevertheless, if your problem involves files or paths or environment values, running strace on the problematic program and redirecting the output to a file and then grepping that file for your path/file/env string may help you see what your program is actually attempting to do, as distinct from what you expected it to.