You can use plt.subplots_adjust to change the spacing between the subplots Link
subplots_adjust(left=None, bottom=None, right=None, top=None, wspace=None, hspace=None)
left = 0.125 # the left side of the subplots of the figure
right = 0.9 # the right side of the subplots of the figure
bottom = 0.1 # the bottom of the subplots of the figure
top = 0.9 # the top of the subplots of the figure
wspace = 0.2 # the amount of width reserved for blank space between subplots
hspace = 0.2 # the amount of height reserved for white space between subplots