<script type="text/javascript">
function MyFunction() {
var FNumber = Number(document.getElementById('txtFirstNumber').value);
var SNumber = Number(document.getElementById("txtSecondNumber").value);
var Sum = FNumber + SNumber;
alert(Sum);
}
</script>
<table class="auto-style1">
<tr>
<td>FirstNaumber</td>
<td>
<asp:TextBox ID="txtFirstNumber" runat="server"></asp:TextBox>
</td>
</tr>
<tr>
<td>SecondNumber</td>
<td>
<asp:TextBox ID="txtSecondNumber" runat="server"></asp:TextBox>
</td>
</tr>
<tr>
<td> </td>
<td>
<asp:TextBox ID="txtSum" runat="server"></asp:TextBox>
</td>
</tr>
<tr>
<td> </td>
<td>
<asp:Button ID="BtnSubmit" runat="server" Text="Submit" OnClientClick="MyFunction()" />
</td>
</tr>
</table>
</div>
</form>