What you asked for is:
IF OBJECT_ID('tempdb..##CLIENTS_KEYWORD') IS NOT NULL
BEGIN
DROP TABLE ##CLIENTS_KEYWORD
CREATE TABLE ##CLIENTS_KEYWORD(client_id int)
END
ELSE
CREATE TABLE ##CLIENTS_KEYWORD(client_id int)
IF OBJECT_ID('tempdb..##TEMP_CLIENTS_KEYWORD') IS NOT NULL
BEGIN
DROP TABLE ##TEMP_CLIENTS_KEYWORD
CREATE TABLE ##TEMP_CLIENTS_KEYWORD(client_id int)
END
ELSE
CREATE TABLE ##TEMP_CLIENTS_KEYWORD(client_id int)
Since you're always going to create the table, regardless of whether the table is deleted or not; a slightly optimised solution is:
IF OBJECT_ID('tempdb..##CLIENTS_KEYWORD') IS NOT NULL
DROP TABLE ##CLIENTS_KEYWORD
CREATE TABLE ##CLIENTS_KEYWORD(client_id int)
IF OBJECT_ID('tempdb..##TEMP_CLIENTS_KEYWORD') IS NOT NULL
DROP TABLE ##TEMP_CLIENTS_KEYWORD
CREATE TABLE ##TEMP_CLIENTS_KEYWORD(client_id int)