You can use the npm modules jsdom and htmlparser to create and parse a DOM in Node.JS.
Other options include:
Out of all these options, I prefer using the Node.js option, because it uses the standard W3C DOM accessor methods and I can reuse code on both the client and server. I wish BeautifulSoup's methods were more similar to the W3C dom, and I think converting your HTML to XHTML to write XSLT is just plain sadistic.