WARNING: setting this value too high may cause your system to experience a significant hiccup. The higher the value you set, the more virtual memory is allocated to the screen process when initiating the screen session. I set my ~/.screenrc to "defscrollback 123456789" and when I initiated a screen, my entire system froze up for a good 10 minutes before coming back to the point that I was able to kill the screen process (which was consuming 16.6GB of VIRT mem by then).