@RobinL as mentioned in previous comments, you can use chart.series[n].setData(). First you need to make sure you’ve assigned a chart instance to the chart variable, that way it adopts all the properties and methods you need to access and manipulate the chart.
I’ve also used the second parameter of setData() and had it false, to prevent automatic rendering of the chart. This was because I have multiple data series, so I’ll rather update each of them, with render=false, and then running chart.redraw(). This multiplied performance (I’m having 10,000-100,000 data points and refreshing the data set every 50 milliseconds).