As per matplotlib's suggestion for image grids:
import matplotlib.pyplot as plt
from mpl_toolkits.axes_grid1 import ImageGrid
fig = plt.figure(figsize=(4., 4.))
grid = ImageGrid(fig, 111, # similar to subplot(111)
nrows_ncols=(2, 2), # creates 2x2 grid of axes
axes_pad=0.1, # pad between axes in inch.
)
for ax, im in zip(grid, image_data):
# Iterating over the grid returns the Axes.
ax.imshow(im)
plt.show()