If we have no entries in log files then we can try to debug apache2 using this command:
$ apache2 -S
or
$ apache2 -e debug
Possible output:
[Fri Apr 05 04:04:59.682880 2019] [core:warn] [pid 11086] AH00111: Config variable ${APACHE_RUN_DIR} is not defined
apache2: Syntax error on line 80 of /etc/apache2/apache2.conf: DefaultRuntimeDir must be a valid directory, absolute or relative to ServerRoot