[python] How to remove gaps between subplots in matplotlib?

Another method is to use the pad keyword from plt.subplots_adjust(), which also accepts negative values:

import matplotlib.pyplot as plt

ax = [plt.subplot(2,2,i+1) for i in range(4)]

for a in ax:
    a.set_xticklabels([])
    a.set_yticklabels([])

plt.subplots_adjust(pad=-5.0)

Additionally, to remove the white at the outer fringe of all subplots (i.e. the canvas), always save with plt.savefig(fname, bbox_inches="tight").