If anyone is using Visual Studio 2017 and IIS and is trying to debug a web site project, the following worked for me:
inetpub/wwwroot
directory.http(s)://localhost/(web site name as appears in IIS)
for example: http://localhost/MyWebSite
That's it! Don't forget to make sure the web site is running on the IIS and that the web site you wish to debug is selected as the startup project (Right-click -> Set as StartUp Project).
Original post: How to Debug Your ASP.NET Projects Running Under IIS