If you want to set only one specific class, you might write a TypeScript function returning a boolean to determine when the class should be appended.
TypeScript
function hideThumbnail():boolean{
if (/* Your criteria here */)
return true;
}
CSS:
.request-card-hidden {
display: none;
}
HTML:
<ion-note [class.request-card-hidden]="hideThumbnail()"></ion-note>