Taken from this tutorial, with corrections made thanks to the top comment:
function getMousePos( canvas, evt ) {
var rect = canvas.getBoundingClientRect();
return {
x: Math.floor( ( evt.clientX - rect.left ) / ( rect.right - rect.left ) * canvas.width ),
y: Math.floor( ( evt.clientY - rect.top ) / ( rect.bottom - rect.top ) * canvas.height )
};
}
Use on a canvas as follows:
var canvas = document.getElementById( 'myCanvas' );
canvas.addEventListener( 'mousemove', function( evt ) {
var mousePos = getMousePos( canvas, evt );
} );