@Autowired + @Qualifier will work only with spring DI, if you want to use some other DI in future @Resource is good option.
other difference which I found very significant is @Qualifier does not support dynamic bean wiring, as @Qualifier does not support placeholder, while @Resource does it very well.
For example: if you have an interface with multiple implementations like this
interface parent {
}
@Service("actualService")
class ActualService implements parent{
}
@Service("stubbedService")
class SubbedService implements parent{
}
with @Autowired & @Qualifier you need to set specific child implementation like
@Autowired
@Qualifier("actualService") or
@Qualifier("stubbedService")
Parent object;
which does not provide placeholder while with @Resource you can put placeholder and use property file to inject specific child implementation like
@Resource(name="${service.name}")
Parent object;
where service.name is set in property file as
#service.name=actualService
service.name=stubbedService
Hope that helps someone :)