My solution uses positioning to get wrapped lines automatically line up correctly. So you don't have to worry about setting padding-right on the li:before.
ul {_x000D_
margin-left: 0;_x000D_
padding-left: 0;_x000D_
list-style-type: none;_x000D_
}_x000D_
_x000D_
ul li {_x000D_
position: relative;_x000D_
margin-left: 1em;_x000D_
}_x000D_
_x000D_
ul li:before {_x000D_
position: absolute;_x000D_
left: -1em;_x000D_
content: "+";_x000D_
}
_x000D_
<ul>_x000D_
<li>Item 1 Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam</li>_x000D_
<li>Item 2 Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam</li>_x000D_
<li>Item 3 Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam</li>_x000D_
<li>Item 4</li>_x000D_
<li>Item 5</li>_x000D_
</ul>
_x000D_