[asp.net] Could not load file or assembly or one of its dependencies. Access is denied. The issue is random, but after it happens once, it continues

If you are using impersonation, be sure to give permissions, including write and modify permission to the relevant user account on the following folder:

C:\Users\[username]\AppData\Local\Temp\Temporary ASP.NET Files

I was missing the modify permission, which was why just adding the default permissions wasn't working for me.

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