Vertical alignment doesn't work with floated elements, indeed. That's because float lifts the element from the normal flow of the document. You might want to use other vertical aligning techniques, like the ones based on transform, display: table, absolute positioning, line-height, js (last resort maybe) or even the plain old html table (maybe the first choice if the content is actually tabular). You'll find that there's a heated debate on this issue.
However, this is how you can vertically align YOUR 3 divs:
.wrap{
width: 500px;
overflow:hidden;
background: pink;
}
.left {
width: 150px;
margin-right: 10px;
background: yellow;
display:inline-block;
vertical-align: middle;
}
.left2 {
width: 150px;
margin-right: 10px;
background: aqua;
display:inline-block;
vertical-align: middle;
}
.right{
width: 150px;
background: orange;
display:inline-block;
vertical-align: middle;
}
Not sure why you needed both fixed width, display: inline-block and floating.