You should install IIS sub components from
Control Panel
-> Programs and Features
-> Turn Windows features on or off
Internet Information Services
has subsection World Wide Web Services
/ Application Development Features
There you must check ASP.NET
(.NET Extensibility
, ISAPI Extensions
, ISAPI Filters
will be selected automatically). Double check that specific versions are checked. Under Windows Server 2012 R2, these options are split into 4 & 4.5.
Run from cmd
:
%windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_regiis.exe -ir
Finally check in IIS manager, that your application uses application pool with .NET framework version v4.0.
Also, look at this answer.